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Is ActiveCampaign HIPAA Compliant?

Email HIPAA Compliance

ActiveCampaign is a cloud-based marketing automation platform that helps organizations manage their email marketing, customer relationships, and sales automation, and it can be HIPAA compliant for enterprise deployments. The platform’s automation capabilities enable organizations to streamline their workflows and carry out marketing campaigns with less administrative overhead, saving both time and money. Additionally, ActiveCampaign’s advanced segmentation tools allow companies to personalize campaigns according to demographics, behavior, and past interactions.

While these capabilities are highly sought after by healthcare organizations who want to enhance their engagement with patients and customers, they require one characteristic above all in their marketing platform of choice: HIPAA compliance.

More specifically, for a company to send electronic protected health information (ePHI) through an email marketing platform, it must comply with the Health Insurance Portability and Accountability Act (HIPAA).

Let’s take a closer look…

Is ActiveCampaign HIPAA Compliant?

Firstly, to address the question directly – is ActiveCampaign HIPAA compliant? – it is not HIPAA-compliant by default. Healthcare organizations can only conduct HIPAA compliant marketing campaigns if they are signed up for the Enterprise version of the solution.

Our findings revealed that companies are required to configure ActiveCampaign accordingly to ensure HIPAA compliance. Again, that healthcare organizations need to ensure compliance themselves – and how they do so – isn’t made 100% clear in any of the company’s literature.

ActiveCampaign’s Security Features

ActiveCampaign does not provide message-level encryption for outbound campaign emails (e.g., portal-based pickup or enforced encryption to recipients), so you generally should not put PHI in the body of campaign emails. This limits your ability to engage patients with personalized and relevant messages that result in more opens, clicks and conversions.ActiveCampaign’s sole mention of HIPAA compliance is on their security features page, on which they state:

“ActiveCampaign is heavily focused on GDPR, SOC 2, and HIPAA compliance. We constantly improve our security to go above and beyond compliance standards.”

Now, while they don’t go into further detail, ActiveCampaign does indeed feature some security controls that lend themselves towards HIPAA compliance. These include:

  • Single Sign-On (SSO): users can sign into ActiveCampaign through an existing identity provider, such as Google, without requiring a separate set of credentials. This helps protect data through stronger access control and allows for simpler user authentication.
  • Multi-Factor Authentication (MFA): ActiveCampaign supports MFA, requiring users to verify their identity through text or time-based one-time password (TOTP) authentication. This adds another layer of security, in line with HIPAA regulations, and is something that could be more emphasized if changes to the Security Rule come into effect later this year. 
  • Automatic Session Timeouts: idle sessions are automatically logged out after a short amount of time: protecting them from session hijacking and related cyber threats. 

Additionally, users are responsible for setting up the proper email authentication protocols themselves, including:

  • SPF (Sender Policy Framework): Specifies authorized mail servers for your domain.DKIM (DomainKeys Identified Mail): Adds a digital signature to your emails, verifying their authenticity.DMARC (Domain-based Message Authentication, Reporting & Conformance): Provides instructions to email providers on handling messages that fail SPF or DKIM checks.

Setting up these protocols helps fight against email spoofing and phishing attacks, ensuring that your emails are recognized as legitimate by recipients’ mail servers.

Will ActiveCampaign Sign a BAA?

Now, even with some security features and stating they are focused on compliance, a marketing platform can’t truly comply with HIPAA regulations unless they sign a Business Associate Agreement (BAA).

ActiveCampaign’s BAA availability appears limited and may depend on plan level; confirm directly with ActiveCampaign.

Discover HIPAA Compliant Alternatives to ActiveCampaign

As this post illustrates, while it is possible to make ActiveCampaign HIPAA compliant, it’s not straightforward. Fortunately, there are alternative email and marketing solutions that are fully HIPAA-compliant – out-of-the-box – removing the guesswork and ambiguity from securing your digital communications and allowing you to focus on engaging with your patients and customers. This includes LuxSci Secure Marketing, which enables healthcare organizations to proactively reach patients and customers with HIPAA compliant email marketing campaigns that can securely include PHI for increased engagement, lead generation and sales.

Discover how LuxSci can elevate your secure healthcare engagement efforts with PHI data, resulting in better health outcomes for your patients, in addition to enhancing your brand identity and achieving your company’s growth objectives. Reach out today for a call or demo.

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LuxSci G2 2026

LuxSci Earns 19 G2 Spring 2026 Badges

LuxSci continues its strong performance in the G2 Spring 2026 Reports, earning 19 badges that reflect real customer satisfaction and consistent product excellence across multiple areas, including email encryption, HIPAA compliant messaging, email security and email gateways.

G2: A Highly Reputable Peer Review Platformn

In a crowded software landscape, it’s easy for bold claims to blur together. That’s where G2 stands apart. Its rankings are based entirely on verified user feedback, giving buyers a clearer picture of how solutions actually perform in day-to-day use, not just how they’re marketed.

For Spring 2026, LuxSci earned recognition across multiple categories, including Leader, Best Customer Support, and Best ROI. Together, these awards show that LuxSci delivers leading technology and a best-in-class customer experience.

What the Badges Represent

Each G2 badge reflects direct input from customers using LuxSci in real-world environments. These evaluations cover usability, onboarding, support responsiveness, and long-term value. LuxSci’s Spring 2026 badges span leadership, customer satisfaction, ROI, and ease of implementation, demonstrating consistent strength across the full customer lifecycle.

Leader Badge: Market Leadership Validated

The Leader badge is awarded to companies with high customer satisfaction and strong market presence. LuxSci’s placement reflects reliable performance, strong security, and continued trust from organizations operating in highly regulated environments like healthcare.

Best Customer Support: A Standout Strength

In secure healthcare communications, timely and accurate support is essential. Issues must be resolved quickly to avoid operational or compliance risks. Customers consistently highlight LuxSci’s fast response times, deep expertise, and a hands-on approach, showing that our technology and our people deliver meaningful, real-world solutions.

Best ROI: Proven Business Value

ROI includes reduced compliance risk, improved efficiency, and scalable operations, not just cost. Customers report measurable benefits from LuxSci’s reliability, built-in compliance, and streamlined workflows, leading to strong long-term value and a solution that keeps you ahead of security and compliance risks.

What This Means for LuxSci Customers

These awards show LuxSci’s ability to serve organizations of varying sizes, from mid-market to enterprise. All reviews are from verified users, ensuring authenticity and transparency. Customers consistently mention reliability, security, and responsive support, along with overall peace of mind. The recognitions validate LuxSci’s ability to deliver secure, dependable communication solutions backed by strong support, including HIPAA compliant email, marketing and forms.

LuxSci’s 10 G2 Spring 2026 badges—including Leader, Best Customer Support, and Best ROI—demonstrate consistent excellence across performance, usability, and customer satisfaction. These results reinforce its position as a trusted provider in secure communications.

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LuxSci MFA

Traditional MFA No Longer Qualifies as “Reasonable” Security

For years, multi-factor authentication (MFA) was considered one of the most effective ways to protect sensitive systems. By requiring a second verification step, such as a text message code or push notification, organizations could significantly reduce the risk of compromised passwords.

But the threat landscape has changed.

Today, attackers routinely bypass traditional MFA using techniques such as MFA evasion, token replay attacks, and consent phishing. These methods are no longer rare or highly sophisticated. They are widely used, automated, and increasingly effective.

As a result, regulators, auditors, and security frameworks are raising expectations for authentication security. For healthcare organizations in particular, traditional MFA alone may no longer satisfy the HIPAA requirement to implement “reasonable and appropriate safeguards.”

In the near future, email systems that rely only on basic MFA, without conditional access or phishing-resistant authentication, may increasingly be viewed as security gaps during risk assessments.

Why Traditional MFA Is No Longer Enough

Traditional MFA still improves security compared to passwords alone. However, many common MFA methods were designed before today’s phishing techniques and cloud authentication attacks became widespread.

Common MFA methods include:

  • SMS verification codes
  • Email-based authentication codes
  • Push notifications to mobile apps

While these mechanisms add friction for attackers, they can still be intercepted or manipulated during sophisticated phishing attacks. Because modern attackers now target authentication workflows directly, organizations relying solely on traditional MFA may be more vulnerable than they realize.

How Attackers Bypass MFA Today

Cybercriminals increasingly rely on tools that capture credentials and authentication tokens during login sessions. Three attack techniques are now especially common.

  • MFA Evasion and Phishing Proxies – Attackers frequently deploy adversary-in-the-middle phishing kits that sit between the user and the real login service. When users enter their credentials and MFA code on a phishing page, the attacker forwards the information to the legitimate site and captures the authentication session. The user successfully logs in—but the attacker gains access as well. If attackers capture those tokens, they can reuse them to access the account directly.
  • Token Replay Attacks – After successful authentication, systems typically issue session tokens that allow users to remain logged in without repeated MFA prompts. This technique has been widely observed in attacks targeting cloud email platforms such as Microsoft 365, allowing attackers to access email data even when MFA is enabled.
  • Consent Phishing – Consent phishing bypasses MFA entirely. Instead of stealing passwords, attackers trick users into granting permissions to malicious applications that request access to their mailbox or files. If users approve the request, the attacker’s application receives persistent access to the account through APIs—often without triggering security alerts.

Why Email Authentication Matters Most in Healthcare

Email remains one of the most critical systems in healthcare organizations. It supports patient communication, internal collaboration, and the exchange of sensitive information. Unfortunately, it is also the most frequently targeted entry point for cyberattacks.

Once attackers gain access to an email account, they can:

  • Impersonate healthcare staff
  • Launch internal phishing attacks
  • Access sensitive patient communications
  • Extract protected health information (PHI)

Because of this, email authentication controls are becoming a major focus for security teams and compliance auditors alike.

Evolving Regulatory Expectations

HIPAA does not prescribe specific technologies, but it requires organizations to implement safeguards that are “reasonable and appropriate” based on risk. As new attack methods emerge, the definition of reasonable security evolves.

Today, many security frameworks and regulatory bodies are emphasizing stronger identity protections, including:

  • Phishing-resistant authentication
  • Conditional access policies
  • Monitoring for suspicious login behavior
  • Controls for third-party application permissions

Organizations that rely solely on basic MFA may increasingly struggle to demonstrate that their authentication protections are sufficient.

The Shift Toward Phishing-Resistant Authentication

To address the weaknesses of traditional MFA, many organizations are adopting phishing-resistant authentication technologies, which can be enabled with tools like Duo and Okta. These solutions rely on cryptographic authentication tied to trusted devices, which prevents attackers from capturing or replaying login credentials.

Examples include:

  • Hardware security keys
  • Passkeys
  • Certificate-based authentication

Because authentication is tied to both the device and the legitimate website domain, these technologies significantly reduce the success rate of phishing attacks.

Why Conditional Access Is Becoming Essential

Conditional access adds another layer of protection by evaluating context and risk before granting access. Instead of treating every login the same, conditional access policies analyze signals such as:

  • Device security status
  • Geographic location
  • Network reputation
  • User behavior patterns

If something appears unusual, such as a login from a new country, the system can require stronger authentication or block the attempt altogether. This risk-based approach to authentication helps prevent many account compromise scenarios.

The Future of HIPAA Risk Assessments

As authentication threats evolve, healthcare security assessments are increasingly focusing on identity protection maturity. Organizations may begin seeing findings related to:

  • Weak or outdated MFA methods
  • Lack of conditional access policies
  • Insufficient monitoring of login activity
  • Unrestricted third-party application permissions

In particular, email systems without advanced authentication protections may be flagged as high-risk vulnerabilities, especially when PHI is accessible.

LuxSci’s Modern Approach to MFA

Modern threats require more than a simple second login factor. LuxSci approaches authentication security with layered identity protection designed specifically for healthcare environments.

Instead of relying solely on basic MFA methods like SMS codes or email verification, LuxSci supports stronger authentication controls and policies that align with evolving security expectations. These protections can include:

  • Strong multi-factor authentication options
  • Monitoring for unusual login behavior
  • Enhanced identity verification mechanisms

By combining multiple security layers within its HIPAA-compliant secure communications email and marketing solutions, LuxSci helps healthcare organizations protect sensitive email communications while maintaining usability for providers, health plan administrators, payment providers, and patient engagement teams.

Conclusion

Multi-factor authentication remains an important security control—but not all MFA is created equal. Attack techniques such as phishing proxies, token replay, and consent phishing have demonstrated that traditional MFA methods can be bypassed. As a result, regulators and auditors are increasingly expecting stronger identity protections.

For healthcare organizations that rely heavily on email communications, the implications are significant. Weak authentication controls can expose sensitive patient data and may soon appear as high-risk findings during HIPAA risk assessments. The organizations best positioned for the future will be those that modernize authentication strategies now, moving toward phishing-resistant methods, conditional access policies, and layered identity protection.

Reach out to LuxSci today to learn how HIPAA compliant email can support both your organization’s engagement and cybersecurity needs.

FAQs

1. What is traditional MFA?

Traditional MFA refers to authentication methods that require a second verification step, typically SMS codes, email codes, or push notifications.

2. Why can attackers bypass MFA today?

Modern phishing tools can intercept authentication sessions or steal login tokens, allowing attackers to access accounts even when MFA is enabled.

3. What is phishing-resistant authentication?

Phishing-resistant authentication uses cryptographic methods tied to trusted devices, preventing attackers from capturing login credentials.

4. Why is email security especially important for healthcare organizations?

Email systems often contain patient communications and sensitive information, making them a common target for cyberattacks.

5. How can organizations improve authentication security?

Organizations can strengthen identity security by adopting phishing-resistant authentication methods, implementing conditional access policies, and monitoring login activity.

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LuxSci Automated Email Encryption

Encryption Optional Email Will Fail Audits in 2026 and Beyond

For years, healthcare organizations have relied on click-to-encrypt email workflows and secure portals as a practical compromise between usability and compliance. Or in some cases, they simply thought most of their emails did not need to be compliant. In regulated industries where data security and privacy are paramount, this approach was still considered “good enough.”

That era is ending.

As we progress into 2026 and beyond, regulators, auditors, and cyber insurers are sending a clear and consistent message: encryption that depends on human choice is no longer acceptable. It’s already happening. Encryption optional email isn’t merely raising concerns, it’s failing audits outright.

An Email Threat Landscape That’s Changing Faster Than Email Habits

Historically, email encryption was treated as a best practice rather than a hard requirement. If an organization could demonstrate that encryption tools existed and that employees had access to them, auditors were often satisfied. The box was checked, everybody moved on.

Today, the questions auditors ask are fundamentally different. Instead of asking whether encryption is available, they are asking whether sensitive data can ever leave the organization unencrypted. If the answer is yes, even in rare cases, or even accidentally, that’s no longer viewed as an acceptable gap. It’s viewed as inadequate control.

Why 2026 Is a Tipping Point for Email Security

Several forces are converging here in 2026 that make optional encryption increasingly untenable. Regulatory scrutiny around PHI and PII exposure continues to intensify. Breach costs and litigation are rising, with email remaining one of the most common vectors for data exposure and breaches. AI is also changing the game for cybercriminals, and attacks will continue to increase and be more sophisticated. As a result, cyber insurers are tightening underwriting requirements and demanding stronger, more predictable controls.

At the same time, email user behavior is unpredictable and inconsistent, which is a non-starter for data security in today’s world.

Taken together, these trends and behaviors point to a single requirement: email security controls must be automated. They must be enforced by systems, not dependent on employee memory, judgment, or good intentions.

The Reality of “Encryption Optional” in Practice

On paper, optional encryption can sound reasonable. In practice, it creates gaps large enough to open you up to a breach.

Secure portals are a good example. They require recipients to click a link, authenticate, and access content in a controlled environment. While this protects data in transit, and is a better approach than no security at all, it also introduces friction. And people don’t like friction. Senders forget to use the portal. Recipients ask for “just a quick email instead.” Shortcuts are taken to save time. And every shortcut becomes a risk.

Click-to-encrypt systems suffer from a similar problem. They rely on users to correctly identify sensitive data and remember to take action. But people often misclassify information, forget to click the button, or assume someone else has already secured the message. From an auditor’s perspective, this isn’t a training failure. It’s a set-up and control failure.

Email Security Defaults Are the New Normal

The latest message from regulators, auditors, and insurers is clear. If encryption is optional, data vulnerabilities become inevitable.

What can you do?

Below is a quick email security checklist to help you get started. Cyber insurers may require or recommend the following safeguards during the underwriting process, such as:

  • Multi-factor authentication (MFA)
  • Endpoint protection
  • Encrypted backups
  • Incident response planning
  • Encryption protocols for sensitive data in transit and at rest, including PHI in emails

In 2026 and beyond, healthcare organizations and regulated industries will be judged not by what they allow, but by what they prevent. Automated, encrypted email is the new. normal.

Want to learn more about LuxSci HIPAA compliant email? Reach out today.

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LuxSci Oiva Health

LuxSci and Oiva Health Combine to Form Transatlantic Healthcare Communications Group

Boston & Helsinki, February 12, 2026 – LuxSci, a provider of secure healthcare communications solutions in the United States, and Oiva Health, a Nordic provider of Digital Care solutions in social and healthcare services, today announced that the companies are joining forces. Backed by Main Capital Partners (“Main”), the combination brings together two complementary platforms and teams, forming a strong transatlantic software group focused on secure healthcare communications.

Founded in 1999, LuxSci is a U.S. provider of HIPAA‑compliant, secure email, marketing, and forms solutions. Its application and infrastructure software enable organizations to securely deliver personalized, sensitive data at scale to support a broad range of healthcare communications and workflows including care coordination, benefits and payments, marketing, wellness communications, after care and ongoing care. Certified by HITRUST for the highest levels of data security, LuxSci serves dozens of healthcare enterprises and hundreds of mid‑market organizations.

Founded in 2010, Oiva Health is a provider of digital care and communications solutions in the Nordics. Headquartered in Finland, with additional offices in Denmark, Norway, and Sweden, Oiva Health offers digital care and digital clinic solutions – including digital visits, secure messaging, online scheduling and appointments, and caregiver communications – serving the long-term care, especially elderly care, and occupational healthcare verticals. The company employs approximately 60 people and has recently expanded across the Nordic region, with a growing presence in Norway and Sweden.

The combination of LuxSci and Oiva Health creates a larger, cross Atlantic group with complementary solutions, serving the U.S. and European markets. Together, the companies offer healthcare providers, payers, and suppliers a comprehensive suite of tools to communicate securely and compliantly, spanning communications, workflows, and virtual care delivery.

Daan Visscher, Partner and Co-Head North America at Main, commented: “We are pleased to announce this cross Atlantic transaction, creating an internationally active secure communications player within the healthcare and home care space. The combined product suite enables healthcare organizations to drive much needed efficiency gains in healthcare provision addressing a global trend of rising costs, aging population, and increasing pressure on resources needed to provide high-quality care.”

Mark Leonard, CEO of LuxSci, said, “We are thrilled to join forces with Oiva Health and believe that together we can truly make a difference in healthcare coordination, access, and delivery. We see an exciting path forward with our customers benefiting from an end-to-end, secure and compliant approach to optimizing both healthcare communications and today’s frontline workers, which we need now more than ever.”

Juhana Ojala, CEO at Oiva Health, concluded, “We look forward to this new chapter together with LuxSci. We are very excited about the strong alignment between our solutions, which especially strongly positions us to expand our flagship Digital Care offering to the high-potential U.S. care market – from care coordination to care delivery to in-home and institutional care.”

Nothing contained in this Press Release is intended to project, predict, guarantee, or forecast the future performance of any investment. This Press Release is for information purposes only and is not investment advice or an offer to buy or sell any securities or to invest in any funds or other investment vehicles managed by Main Capital Partners or any other person.

[END OF MESSAGE]

About LuxSci

LuxSci is a U.S.-based provider of secure healthcare communications solutions for the healthcare industry. The company offers secure email, marketing, forms and hosting, delivering HIPAA‑compliant communication solutions that enable organizations to safely manage and transmit sensitive data. Founded in 1999, LuxSci serves more than 1,900 customers across healthcare verticals, including providers, payers, suppliers, and healthcare retail, home care providers, and healthcare systems, as well as organizations operating in other highly regulated industries. LuxSci is HITRUST‑certified with example clients being Athenahealth, 1800 Contacts, Lucerna Health, Eurofins, and Rotech Healthcare, among others.

About Oiva Health

Oiva Health is a Digital Care provider in the Nordics, offering a comprehensive Digital Platform for integrated health and care services to digitalize primary healthcare, social care, hospital healthcare and long-term care services. The company was founded in 2010 and currently employs approximately 60 people in Finland, Denmark, Norway, and Sweden serving domestic municipalities, customers and partners, such as City of Helsinki, Keski-Suomi Welfare Region, Länsi-Uusimaa Welfare Region in Finland, and Viborg municipality in Denmark with its Digital Care platform. Annually over 5 million customer contacts are handled digitally through Oiva Health’s Digital Care and Digital Clinic platforms.  

About Main Capital Partners

Main Capital Partners is a software investor managing private equity funds active in the Benelux, DACH, the Nordics, France, and the United States with approximately EUR 7 billion in assets under management. Main has over 20 years of experience in strengthening software companies and works closely with the management teams across its portfolio as a strategic partner to achieve profitable growth and create larger outstanding software groups. Main has approximately 95 employees operating out of its offices in The Hague, Düsseldorf, Stockholm, Antwerp, Paris, and an affiliate office in Boston. Main maintains an active portfolio of over 50 software companies. The underlying portfolio employs approximately 15,000 employees. Through its Main Social Institute, Main supports students with grants and scholarships to study IT and Computer Science at Technical Universities and Universities of Applied Sciences.

The sender of this press release is Main Capital Partners.

For more information, please contact:

Main Capital Partners
Sophia Hengelbrok (PR & Communications Specialist)

sophia.hengelbrok@main.nl

+ 31 6 53 70 76 86

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LuxSci vs. Zix Webroot

LuxSci vs. Zix Webroot: Choosing the Right HIPAA Compliant Email Provider

There are many crucial factors to consider when developing and executing successful healthcare communication campaigns. First and foremost, you must ensure the protected health information (PHI) under your organization’s care is handled securely, as mandated by Health Insurance Portability and Accountability Act (HIPAA) regulations, which begins with selecting the right HIPAA compliant email provider for your company’s needs.

With the right email services provider (ESP) in place, healthcare providers, payers, and suppliers can confidently use PHI in their patient and customer engagement campaigns – safe in the knowledge they’re aligned with HIPAA’s tight regulatory guidelines.

To help you choose the best HIPAA compliant email provider for your healthcare organization’s email outreach objectives, this post compares two of the most well-known HIPAA compliant services on the market: LuxSci and Zix Webroot (from here, simply referred to as Zix). 

Comparing each email provider’s performance on several criteria, we’ll help you decide which solution best fits the needs of your healthcare organization and will help you better engage with your patients and customers. 

LuxSci vs. Zix: Evaluation Criteria

In our evaluation of LuxSci vs. Zix, we’ll be using the following criteria: 

  • Data Security and Compliance: undoubtedly the most important factor when it comes to ensuring HIPAA-compliant email communication within healthcare organizations, this reflects the extent to which each platform secures sensitive patient data as per HIPAA’s regulations. 
  • Performance and Scalability: the email platform’s ability to facilitate high-volume email communication campaigns, which also, subsequently, encompasses the platform’s throughput and how well they’re able to scale in line with an organization’s needs. 
  • Infrastructure: if the email service provider has the necessary security infrastructure in place to both adequately safeguard PHI and support bulk email marketing campaigns.
  • Marketing Capabilities: if the platform provides features that allow you to personalize and refine your patient engagement strategies.
  • Ease of Use: how easy each email service is to use; a deceptively important factor in light of the urgent need for employee cyber threat awareness training. 
  • Other HIPAA-Compliant Products: if the platform offers complementary features that aid healthcare organizations with their broader patient engagement, and growth, objectives. 

Now that we’ve covered the criteria by which we’ll be assessing each email platform, let’s compare LuxSci vs Zix to determine which is the best fit for your company’s needs. 

LuxSci vs. Zix: How Do They Compare?

Data Security and Compliance

LuxSci prides itself on being a fully HIPAA-compliant email service provider, offering end-to-end, flexible, and automated encryption, giving it an advantage in the protection of patient data in the event of its exfiltration by cyber criminals. Additionally, LuxSci is HITRUST-certified, illustrating its additional commitment to data privacy legislation and the securing of PHI. 

Zix is also fully HIPAA-compliant and, consequently, enables the use of PHI to personalize your email communications. That said, Zix doesn’t offer as many encryption options as LuxSci. Most notably, Zix doesn’t enforce Transport Layer Security (TLS) encryption or enable automated encryption. The absence of these features means that a healthcare organization’s security teams must perform more manual oversight when it comes to encryption of PHI, increasing the chance of human error.

Performance and Scalability

While Zix supports large email campaigns and provides detailed reporting functionality, LuxSci is the more prudent choice for high-volume email marketing campaigns. 

LuxSci maintains the necessary infrastructure to ensure the reliable delivery of hundreds of thousands to millions of emails per month (i.e., throughput – 1000s of emails per hour), all while adhering to HIPAA’s strict guidelines on preserving patient privacy.

Infrastructure

In the same way that LuxSci have advantages over Zix on data security capabilities, it performs well in this category too, which makes sense, as the two factors are interwoven. 

While offering a range of customary multi-tenancy infrastructure setups, Zix doesn’t accommodate dedicated, or single-tenancy, infrastructure options – for companies who can’t afford to depend on the security postures of the companies with whom they share servers. Zix, in line with its ability to facilitate large patient or customer engagement campaigns, provides enterprise-scale scalability. 

Zix also provides high availability and robust disaster recovery capabilities, so healthcare organizations can retain their operational capabilities in the event of a cyber attack. Or, alternatively, an unforeseen physical disaster that compromises a company’s infrastructure (power outages, fires, storms, intentional damage, etc.).

That said, LuxSci possesses all these features in addition to more comprehensive single-tenancy options, scalability, and secure email hosting.

Marketing Capabilities

As with our comparisons of LuxSci against email platforms like Paubox and Virtru, it’s somewhat futile to compare each platform’s marketing capabilities – as neither LuxSci or Zix are marketing platforms, in the vein of Adobe Campaign or Oracle Eloqua, for example. 

That said. LuxSci provides a HIPAA compliant marketing solution, offering automation, for streamlining email marketing campaigns, and, personalization options, for more engaging email communication campaigns. 

Ease of Use

Both LuxSci and Zix perform admirably in this category, but the edge goes to Zix, as LuxSci implementations often involve the complexities that come with large-scale, high volume use cases.

LuxSci, however, is known for offering best-in-class customer support backed by HIPAA security experts, honed as a result of over 25 years of facilitating and supporting email communication strategies for healthcare organizations of all sizes. 

Other HIPAA-compliant Products

With secure texting functionality, secure forms for HIPAA compliant data collection, and secure file sharing, LuxSci ranks well in this category.  Zix, in contrast, provides only secure file sharing – though, because of Zix Webroot’s capabilities, offers superior secure file sharing to LuxSci. 

Get Your Copy of LuxSci’s Vendor Comparison Guide

To discover how LuxSci and Zix stack up against the other leading email providers on the market when it comes to HIPAA compliance, take a look at our Vendor Comparison Guide.  Evaluating 12 email delivery platforms, the guide offers comprehensive insights on what to consider when selecting a HIPAA compliant provider, and how to choose the best solution for you.

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HIPAA compliant email

Most Popular LuxSci Blog Posts of 2025

As we close out 2025, healthcare communicators, IT and compliance leaders, and digital marketers face an ever-changing landscape of security threats, regulatory updates, and technology innovations. At LuxSci, we’re committed to helping you with continuous updates and guidance on the future of secure healthcare communications.

In case you missed it, or need a refresh, below are some of our most popular blog posts from 2025. Enjoy!

1. Improve Email Engagement and Marketing Results with Automated Workflows

Automated workflows are transforming how healthcare organizations engage patients and customers — enabling dynamic, event-driven campaigns that easily scale your outreach and keep you HIPAA compliant. In this post, we introduce LuxSci’s Automated Workflows capability for our Secure Marketing healthcare solution. Learn how sequence-based journeys can personalize outreach and optimize engagement with behavior-based triggers that improve campaign performance — without sacrificing data security.

Read the full post: LuxSci Enhances Secure Marketing with Automated Workflows

2. Healthcare Email Threat Readiness Strategies

Email remains a frontline channel for healthcare communications, and a prime target for cyber threats and criminals. This deep-dive into email threat readiness strategies covers essential practices like continuous monitoring, business continuity planning, and workforce training to mitigate email-borne security risks. Whether you’re responsible for clinical systems, marketing, or enterprise IT, this post provides a strategic playbook to strengthen your defenses, while maximizing your results.

Read the full post: Healthcare Email Threat Readiness Strategies

3. HIPAA Compliant Email — 20 Tips in 20 Minutes

For practical guidance you can apply right now, this on-demand webinar distills 20 key tips for HIPAA-compliant email across technical, legal, and operational domains. Whether you’re refining your infrastructure, improving deliverability, or modernizing your data security posture in 2026, this resource is a time-efficient way to elevate your compliance and security.

Read the post and watch the webinar on demand: HIPAA Compliant Email: 20 Tips in 20 Minutes

4. Is SendGrid HIPAA-Compliant? What You Should Know

Choosing the right email provider matters, especially when Protected Health Information (PHI) is at stake. In this post, we examine SendGrid’s capabilities in the context of HIPAA compliance, outline what it takes to send PHI securely, and offer guidance on evaluating third-party services for secure healthcare email and communication needs.

Read the full post: Is SendGrid HIPAA-Compliant?

5. LuxSci Shines in G2 Winter 2026 Reports

Customer feedback matters to LuxSci. In this post, we share the most recent news about LuxSci’s performance in the G2 Winter 2026 Reports, where we earned 20 badges across categories like Email Security, Encryption, Gateway, and HIPAA-Compliant Messaging. These reviews reflect not just product excellence, but trust from real users, which we work hard to build every day!

Read the full post: LuxSci Shines in G2 Winter 2026 Reports

Looking Ahead to 2026

We look forward to providing more information and insights on secure healthcare communications in the coming year, including the latest on HIPAA compliant email, PHI security, healthcare marketing, threat readiness, and personalized engagement. In the meantime, if you’re not already, follow us on LinkedIn below, and we’ll see you here in 2026!

Follow LuxSci on LinkedIn

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LuxSci HIPAA-Compliant Marketing Email

12 Key Questions to Ask Before Sending HIPAA-Compliant Marketing Emails

So – you’ve just been told that your email marketing program is putting your company at risk of violating HIPAA.

Ok. What now?

If you want to continue your email-based patient engagement efforts – without the risk of the financial, operational, and reputational risk that accompanies the exposure of sensitive patient data, you must implement HIPAA compliant email marketing practices.

This is comprised of two components: becoming HIPAA-compliant, setting up the required systems and procedures to ensure your PHI (PHI) and EPHI (EPHI) are protected, and your marketing objectives, who you want to reach and what to communicate.

However, you don’t have to let your marketing objectives suffer for the sake of security.

Implementing a HIPAA-compliant marketing program can actually help you achieve better marketing results.

Asking yourself these 12 questions ensures your email marketing campaigns align with your business goals and are HIPAA-compliant.

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HIPAA-Compliant Marketing Emails

1. Do you have security controls to protect access to your email marketing system?

2. Do you have a documented procedure to guide you HIPAA-compliant email marketing?

3. Can you send encrypted emails?

4. Do you have a complete understanding of your organization’s PHI and ePHI?

5. Do you have a required training process for anyone sending HIPAA-compliant marketing emails?

6. Do you have effective protection against malware?

7. Do you have valid Business Associate Agreements (BAA) in place?

8. Why am I sending this email?

9. Is my email’s subject line standing out?

10. What is the recipient’s brand and product awareness level?

11. Have I tested my message for readability?

12. Have I sent my message to a test email account?

HIPAA-Compliant Marketing Emails

If your organization requires HIPAA-compliant email, start by using these questions to inspect your email marketing for compliance. Note that while we can’t provide legal advice, the below questions will help you identify some of the most common points of vulnerability and non-compliance.

1. Do you have security controls to protect access to your email marketing system?

Email security is an essential component of being HIPAA-compliant. As a starting point, check your internal security processes for access restrictions. This includes:

  • A robust password policy, i.e., changed frequently (e.g., 30 days), has to contain a mixture of characters, etc.
  • Multi-factor authentication (MFA), i.e., users verifying their identity in multiple ways, e.g., username/password and sent number codes (text, email, key fob, etc.), biometrics, etc.
  • Role-based access controls, i.e., granting access to individuals based on the responsibilities of their job role.
  • Zero Trust Architecture (ZTA), i.e., “never trust, always verify” – where users are required to reconfirm their identity on a case-by-case basis, as opposed to once when logging on, which mitigates session hijacking and similar threats.

2. Do you have a documented procedure to guide you HIPAA-compliant email marketing?

“Winging it” simply doesn’t cut it when it comes to HIPAA-compliant email marketing; you must develop a comprehensive documented process detailing how you intend to safeguard PHI throughout your email marketing campaigns.

This should include:

  • Specifying the HIPAA-compliant email delivery service you’ll use to execute your marketing campaigns
  • The processes and controls you’ll use to encrypt data  for ePHI at rest and in transit
  • The access and authentication controls you have in place
  • How you’ll implement data minimization: only using the minimum necessary PHI in communications – and not including sensitive PHI unless it’s essential.
  • How you’ll securely dispose of data: Implement a process for securely deleting emails containing ePHI once they’re no longer needed, to comply with retention policies.
  • Staff training: educating employees involved in email marketing on how to securely handle PHI and other HIPAA requirements.
  • Incident response plan, i.e., an additional documented plan for how you’ll respond to data breaches and other cyber attacks; this also includes notifying any affected parties as mandated by HIPAA.

If you’re starting from scratch, the information contained in the answers to the questions in this article provides a useful starting point for creating your first procedure.

3. Can you send encrypted emails?

If you are sending highly sensitive data or PHI in your emails, be aware that HIPAA requires the data to be encrypted a rest, i.e., the storage medium where it resides, and in transit, when being sent to recipients.

To the surprise of many healthcare organizations, most major email marketing providers, such as Mailchimp and Constant Contact are unable to provide encryption for data in transit and only protect data in their systems. To avoid falling foul of HIPAA regulations, ensure that the email delivery platform you use to transmit messages containing PHI offers end-to-end encryption.

4. Do you have a complete understanding of your organization’s PHI and ePHI?

Much of the time, when we, as well as healthcare providers, talk about PHI, we’re actually referring to electronic protected health information (EPHI). While PHI is a catch-all term to account for all sensitive health information, in truth, in the digital age, the vast majority is stored electronically in data centers – and the patient data handled is EPHI.

You can discover “PHI” and “ePHI” within the context of your organization’s context by identifying and categorizing the PHI and ePHI typically handled in your business. It’s an absolutely crucial tenet of data protection that you simply can’t protect what you’re not aware of.

Comprehensive PHI categorization will help your staff navigate HIPAA-compliant email requirements.

5. Do you have a required training process in place for anyone sending HIPAA-compliant marketing emails?

Your HIPAA compliance program, as with your company’s overall cybersecurity posture, is only as strong as your weakest link. In light of this, it’s essential to educate the staff within your company who are involved in your healthcare engagement campaigns on the secure use of ePHI and HIPAA-compliant marketing practices.

Additionally, this needs to be reflected in your onboarding process, so new hires are made familiar with HIPAA regulations, should their role require it.

6. Do you have effective protection against malware?

In the unlikely event you need any further encouragement to revisit your company’s anti-malware (viruses, ransomware, Trojans, etc.) measures, there are always HIPAA compliance requirements! 

To better protect your sensitive customer data against a slew of increasingly sophisticated cyber threats, start with these three key considerations:

  1. Do you have anti-malware protection running on all of your organization’s devices? Additionally, does this extend to your employee’s personal devices on which they handle PHI?
  2. How frequently do you update your anti-malware solution?
  3. Does your email marketing provider have sufficient protection malware mitigation measures in place, as per HIPAA requirements?

7. Do you have valid Business Associate Agreements (BAA) in place?

It’s normal to outsource activities like email marketing to a third party, but for the service they provide to be HIPAA-compliant, you must have a business associate agreement (BAA) in place.

A BAA documents how two organizations will share PHI and under what circumstances. A BAA also details the legal responsibilities of each party in the event of a serious issue. With a BAA being a core component of HIPAA compliance, failure to have one in place with your email service provider is an immediate HIPAA violation – and one that can result in serious consequences for a healthcare company.

Getting Better Results from HIPAA-Compliant Email Marketing

Now that you’ve confirmed your systems are HIPAA-compliant, let’s move on to making sure your email marketing strategy aligns with your overall business objectives.

In pursuit of this, the following questions serve as a handy “monthly review” for refining the effectiveness of your email-based patient outreach efforts .

8. Why am I sending this email?

First and foremost, for the best results, each email you send should have a single, clearly defined purpose.

I know what you’re thinking – “my customers and patients are smart, they can handle multiple points in a single message.”  And while that’s true, at whatever point your email reaches a recipient, they’re already juggling several different priorities at once. While they’re capable of juggling multiple points in a message – they’re unlikely to want to; when it comes to email marketing, a single goal is the best way to go.

Similarly, it’s important to remember that your email is one of dozens –  or hundreds – received by your patient that day. So, if your message is long and overly complicated, the reader will likely skip over or delete it.

9. Is my email’s subject line standing out?

Following on the above point, is your email subject line impactful enough to stand out amidst the pile of messages that will land in the patient’s inbox that day? The email subject line is the most important part of your email because it’s responsible for persuading the reader to open your message.

Despite this, many marketers still use terrible, ineffective subject lines and wonder why their emails are failing to produce results!

For the best results, write up three to ten subject lines for your next email, step away for 5-10 minutes, and then choose the headline you determine as best.

Consider these examples to check your understanding:

Ineffective Email Subject Lines

  1. Blank (no subject): writing nothing in the subject line
  2. Clinic Newsletter (tell them more, e.g., the subject or theme for the month)
  3. Overusing exclamation marks!!!

Effective Email Subject Lines (examples based on a dental practice)

  1. BRAND-NEW Dental Product Released Today
  2. How to Cut Down on Your Health Insurance Paperwork
  3. [Case Study] How We Helped 3 Ex-Smokers Get White Teeth

10. What is the recipient’s brand and product awareness level?

Whether promoting medical devices, new digital solutions technology, or any healthcare product or service, understanding the prospect’s awareness level is essential.

If your email is designed to introduce a brand-new product, stick to high-level features and benefits while avoiding technical jargon and granular product details. Conversely, if you’re writing an email to experienced, highly knowledgeable readers, going into greater depth makes sense.

Advanced list management and segmentation tools, as offered by Luxsci Secure Marketing, are key for ensuring the communications you send match the reader’s awareness level.

11. Have I tested my message for readability?

Do you know one of the reasons that Hemingway was popular? He   was skilled at writing short phrases and phrases. Consequently, his writing was easy to understand and appealed to a wide variety of people. When in doubt, keep your writing short and free of jargon, abbreviations and “insider” terms.

When you’re deeply involved in the details of your business, it’s so easy to overlook just how much specialized jargon and language you frequently use. However, if you want your communications to engage with patients and customers, they need to be as accessible as possible.

Fortunately, there are simple solutions to this, with tools like the Text Readability Calculator that are designed to quickly enhance the readability of your emails.

12. Have I sent my message to a test email account?

Finally, if you’ve followed all of the above advice, you’re almost ready to hit SEND…there’s just one more thing you need to check.

Determine how your email will look to recipients, including its clarity, and readability by simply sending a test email to one of your own email accounts once it is received.

In particular, pay attention to how the subject line looks and test all the links in the email to ensure they take the reader through to the intended destination, such as a product or service page. A broken link will only frustrate the recipient – who was interested enough to click through, no less – and lower your conversion rate.

Better still, send the test email to a colleague somebody and ask for their opinion about the quality of the message and whether it creates the desired impression.

Demystifying HIPAA-Compliant Email Marketing

As the most experienced HIPAA-compliant email provider, LuxSci specializes in providing secure and HIPAA-compliant solutions for companies aiming to send hundreds of thousands – or millions – of emails. Our hypersegmentation tools allow you to precisely target an unlimited number of patient sub-populations to maximize the efficacy of your messaging.

Are you interested in discovering how LuxSci’s secure email marketing platform will streamline your healthcare engagement efforts?

Contact us to learn more about our products and pricing.

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HIPAA Compliance and Email Communications

How Does HIPAA Compliance and Email Communications Work?

HIPAA compliance and email communications require healthcare organizations to implement administrative, physical, and operational safeguards that protect patient information during electronic transmission and storage. Federal regulations mandate encryption protocols, access controls, audit logging, and business associate agreements for all email systems handling protected health information. Healthcare providers must balance security requirements with operational efficiency, ensuring that email communications enhance patient care without creating compliance vulnerabilities or exposing organizations to regulatory penalties.

Safeguards for Email Security

Policy development establishes the framework for how healthcare organizations handle patient information through email channels. Written policies must specify who can send patient data via email, what types of information are appropriate for electronic transmission, and what approval processes govern sensitive communications. Documentation requirements ensure that policies reflect current regulatory standards and organizational practices.

Training programs prepare healthcare staff to use email systems securely while maintaining patient privacy throughout all communications. Education should cover encryption activation procedures, recipient verification methods, and content appropriateness criteria that prevent inadvertent disclosures. New employee training timelines ensure staff understand email security requirements before accessing patient information systems.

Access management procedures control which staff members can use email systems to communicate about patients and what information they can access. Permission structures should align with job functions, ensuring that billing staff, clinical providers, and administrative personnel each have appropriate access levels. Regular access reviews identify outdated permissions that should be revoked when staff change roles or leave organizations.

Security incident procedures outline how organizations respond when email security breaches occur or when staff discover potential vulnerabilities. Response protocols should include immediate containment steps, breach scope assessment methods, and notification procedures for affected patients and regulatory authorities. Documented incident handling demonstrates organizational preparedness during compliance audits.

Encryption Standards That Meet Regulatory Requirements

Transport-level encryption protects email messages during transmission between servers, creating secure channels that prevent interception while communications travel across public networks. TLS 1.2 or higher protocols establish encrypted connections that meet current security standards for protecting healthcare data. Server certificates verify the identity of receiving systems before allowing message transmission to prevent misdirected communications.

Message-level encryption converts email content into unreadable code before transmission, ensuring that only intended recipients with proper decryption keys can access patient information. AES 256-bit encryption provides strong protection that satisfies regulatory expectations for securing electronic protected health information. Automatic encryption removes reliance on manual activation that busy healthcare staff might forget during patient care activities.

Storage encryption protects archived email communications containing patient information while messages reside on servers or backup systems. Encryption at rest prevents unauthorized access if physical storage devices are stolen or improperly disposed. Key management protocols ensure that encryption keys receive the same protection as the data they secure.

Digital signatures add authentication layers that verify message origin and detect any unauthorized modifications during transmission. Certificate-based systems confirm sender identity before allowing message delivery, reducing risks that fraudulent communications might compromise patient information. HIPAA compliance and email communications depend on multiple encryption layers working together to protect data throughout its lifecycle.

Access Controls and Authentication Mechanisms

Multi-factor authentication strengthens account security by requiring users to provide multiple forms of identification before accessing email systems containing patient data. Passwords combined with mobile verification codes, biometric scans, or hardware tokens create barriers that prevent unauthorized access even when credentials are compromised. Authentication strength should match the sensitivity of patient information accessible through email systems.

User provisioning processes establish email accounts for new staff members while defining their access permissions based on job functions and patient care relationships. Automated provisioning systems integrated with human resources databases ensure that access aligns with employment status and role requirements. Termination procedures immediately revoke access when employment ends to prevent former staff from accessing patient communications.

Session controls automatically log users out after inactivity periods, preventing unauthorized access from unattended workstations in busy healthcare environments. Timeout durations should balance security needs with operational efficiency, allowing sufficient time for thoughtful message composition without creating excessive vulnerability windows. Concurrent session monitoring detects unusual login patterns that might indicate account compromise.

Audit capabilities track all email system activities including message transmission, viewing, forwarding, and deletion actions performed by users. Comprehensive logs capture timestamps, user identities, and specific actions taken with patient information. Log retention periods should meet regulatory requirements while supporting security investigations and compliance demonstrations.

BAA Requirements

Contractual obligations between healthcare organizations and email service providers establish responsibilities for protecting patient information during transmission and storage. Written agreements must address encryption standards, security incident notification timelines, and data handling procedures when business relationships terminate. Liability provisions allocate financial responsibilities when breaches result from provider negligence or system failures.

Vendor security assessments verify that email providers maintain appropriate safeguards before organizations entrust them with patient communications. Evaluation procedures should examine provider certifications, data center security, and incident response capabilities. Due diligence documentation demonstrates that organizations selected vendors carefully rather than accepting inadequate security measures.

Performance monitoring ensures that providers maintain contracted security standards throughout business relationships. Regular audit report reviews, security assessment updates, and compliance certification renewals verify ongoing provider commitment to protecting healthcare information. Performance issues should trigger immediate corrective action discussions to prevent security degradation.

Subcontractor management addresses situations where email providers use third-party services for hosting, backup, or support functions. Agreements should require providers to obtain equivalent security commitments from subcontractors who might access patient information. Healthcare organizations need visibility into the complete chain of entities handling their patient communications.

Documentation and Compliance Evidence

Security configuration documentation records the specific settings that organizations implement to protect email communications containing patient information. Configuration records should detail encryption algorithms, authentication requirements, access control structures, and audit logging parameters. Documentation updates track changes over time, creating histories that support compliance demonstrations.

Training records demonstrate that organizations educate staff about secure email practices and HIPAA compliance and email communications requirements. Documentation should include training dates, participant names, content covered, and assessment results verifying comprehension. Record retention periods should extend beyond individual employment to support long-term compliance evidence.

Risk assessment documentation identifies vulnerabilities in email systems and describes mitigation measures implemented to reduce security threats. Assessment reports should evaluate encryption strength, access control effectiveness, and potential failure points that could compromise patient information. Annual assessment updates track how organizations adapt security measures as threats evolve.

Incident reports document security breaches involving email communications and describe organizational responses to contain damage and prevent recurrence. Detailed breach records should include discovery methods, scope determinations, notification procedures, and corrective actions implemented. Incident documentation provides evidence of appropriate breach handling during regulatory investigations.

Operational Considerations and Best Practices

Content appropriateness guidelines help staff determine which patient information is suitable for email transmission versus what requires more secure communication methods. Routine appointment confirmations and general health education may be appropriate for encrypted email while complex diagnoses warrant telephone or in-person discussions. Emergency communications should never rely solely on email that patients might not check promptly.

Recipient verification procedures ensure staff confirm email addresses before transmitting patient information to prevent misdirected communications. Double-check processes, automated address validation, and recent communication history reviews reduce human errors that could expose patient data. Organizations should implement technological controls that flag external recipients when sending patient information.

Mobile device management addresses security challenges when staff access email from smartphones and tablets outside secure healthcare facilities. Device encryption, remote wipe capabilities, and containerization technologies separate work communications from personal data on employee devices. Bring-your-own-device policies must ensure that personal devices meet organizational security standards before allowing patient information access.

Retention management balances regulatory requirements to preserve email communications with operational needs to manage storage capacity efficiently. Automated retention policies should archive messages for required periods while deleting expired communications to minimize data exposure risks. Legal hold procedures must override automated deletion when litigation or investigations require communication preservation.

Understanding HIPAA compliance and email communications enables healthcare organizations to leverage digital communication benefits while protecting patient privacy and avoiding regulatory penalties that could result from security failures or policy violations.

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